STARWEST 2020 Keynote : It's In Your DNA, or Is It? The Journey of Testing Software for DNA Analysis

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Thursday, October 8, 2020 - 8:30am to 9:30am

It's In Your DNA, or Is It? The Journey of Testing Software for DNA Analysis

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DNA contains our genetic code and for each individual it's unique. The DNA of any 2 humans is 0.1% different on average, the difference may seem insignificant but it isn't. To be specific, one letter change in just the right place in a code of 6.4 billion letters of your DNA can cause a genetic disease. DNA analysis today is performed across the globe and is used to understand how to build better crops, how coronavirus impacts us, and how can we treat cancer. Given the wide range of applications, the task of identifying significant pieces of information in this BIG DATA set is performed using data analysis techniques ranging from statistical methods to machine learning. Join Aprajita Mathur as she shares her journey of testing bioinformatics applications and how core quality and testing principles are applied to test complex data analysis software. Learn about common challenges like environments, continuous integration and data integrity, and new testing challenges like building novel datasets and testing statistical models that this industry faces and approaches to solve them.

Aprajita Mathur
Guardant Health

Aprajita Mathur is a Senior Bioinformatics Software Test Manager with an engineering background in Bioinformatics. She has more than 10+ years of software testing experience. She has worked as a manual and automation tester on a wide range of products like instrument software, LIMS, web- applications, integrated solutions and data analysis pipelines which are used in the fields of agriculture, transplant genomics, forensics and oncology. Currently she leads the Bioinformatics Software Test team at Guardant Health, which builds the world’s leading comprehensive liquid biopsy. This non-invasive tool for accessing and sequencing tumor DNA is used by oncologists to help advanced cancer patients. She has recently started a chapter for “Women Who Test” in the bay area and hopes to grow this community. In her spare time, she loves to spend time with her family and write new songs for her son.